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Some patients experience several migraines monthly which has a large impact on their quality of life as well contributes to them missing work. If you are having several migraines monthly it may make sense to be on a preventative to reduce the frequency as well as severity of migraines. Preventive treatments may not get rid of the migraines completely but it will take the edge off so you can continue to be active.

There are a variety of different medications that can help with the prevention of migraines. They include the following classes:

  • Blood Pressure Medications
  • Antidepressants
  • Anti-Seizure Medications
  • Botox Injections
  • Calcitonin gene-related peptide monoclonal antibodies (CRGP)

For the purpose of this blog though I am going to concentrate on Herbal alternatives for the prevention of migraines.

Herbal Preventatives

Neutraceuticals are a natural means to treat headaches including migraine. The research is mounting that select supplements can be a safe and effective treatment for headaches. Medical Specialists at Body Restoration and the pharmacists at iCare Pharmacy have put together an optimized package that is cost conscious and based on the evidence in the research literature.

Ask us if this is right for you.


Numerous studies suggest the presence of mitochondrial energy depletion in patients with migraine. Riboflavin, a vitamin that acts as a cofactor in oxidation reduction reactions of flavoproteins during the Krebs cycle and the electron transport chain, plays a vital role in mitochondrial energy production.

Coenzyme Q10

Based on the evidence that migraine is associated with mitochondrial energy depletion and failure, CoQ10, an electron carrier in the electron transport chain, has been evaluated for migraine prevention as it is an important co-factor in sustaining mitochondrial energy stores.


Magnesium is a mechanism of action. It binds to and inhibits N-methyl-D-aspartate (NMDA) glutamate receptors. Multiple studies demonstrate low magnesium in patients with migraine in brain, serum, and saliva, possibly contributing to neuronal hyperexcitability mediated through excess glutamatergic neurotransmission.


Petasites hybridus (butterbur shrub), also called pestilence wort, was used in the Middle Ages to treat the plague. Petasites has antihistamine properties and inhibits leukotriene synthesis. Petasites formosanus (same genus) inhibits calcium channels, another potential mode of action for migraines.


Feverfew supplements typically use dried feverfew leaves, but some supplements use the flowers and stems of the plant. It is believed that the substance in feverfew called parthenolide may help prevent migraine attacks by reducing inflammation or by stopping the aggregation of platelets.

Should you use one? Which one?

These are some options available to you in the management of your migraines. Please consult with one of our pharmacists to see what options are best for you in the prevention and management of your migraines.

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